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Symbol
Name
ID
Fzd4
frizzled class receptor 4
MGI:108520
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Vitreous hemorrhage
Peripheral retinal avascularization
Retinal neovascularization
Disease(s) Associated with FZD4
exudative vitreoretinopathy 1

Mouse Phenotypes
cardiovascular system phenotype
abnormal brain vasculature morphology
abnormal retina vasculature morphology
abnormal stria vascularis vasculature morphology
abnormal vascular development
decreased angiogenesis
hemorrhage
retina hemorrhage
Availability Mouse Genotype
Fzd4tm1.1Lex/Fzd4tm1.1Lex *
Fzd4tm1Nat/Fzd4tm1Nat
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(Tek-cre)1Ywa/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory